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Target
Protachykinin-1
Ligand
BDBM50281563
Substrate
n/a
Ki
0.5±n/a nM
Comments
PDSP_1488
Citation
 Burcher, E; Buck, SH; Lovenberg, W; O'Donohue, TL Characterization and autoradiographic localization of multiple tachykinin binding sites in gastrointestinal tract and bladder. J Pharmacol Exp Ther 236:819-31 (1986) [PubMed] 
Target
Name:
Protachykinin-1
Synonyms:
Nka | Nkna | Protachykinin-1 | Substance K | Substance P | TKN1_RAT | Tac1 | Tac2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
15007.06
Organism:
RAT
Description:
Substance K 0 RAT::P06767
Residue:
130
Sequence:
MKILVAVAVFFLVSTQLFAEEIGANDDLNYWSDWSDSDQIKEAMPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRRK
  
Inhibitor
Name:
BDBM50281563
Synonyms:
CHEMBL414786 | pGlu-Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2 | physalaemin
Type:
Small organic molecule
Emp. Form.:
C58H84N14O16S
Mol. Mass.:
1265.437
SMILES:
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)C1CCC(=O)N1)C(N)=O
Structure:
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