Reaction Details Report a problem with these data
Target
Alpha-1A adrenergic receptor
Ligand
BDBM50016897
Substrate
n/a
Ki
37±n/a nM
Comments
PDSP_544
Citation
 Jones, SB; Smith, JM; Jones, AW; Bylund, DB Alpha-1 adrenergic receptor binding in aortas from rat and dog: comparison of [3H]prazosin and beta-iodo-[125I]-4-hydroxyphenyl-ethyl-aminomethyl-tetralone. J Pharmacol Exp Ther 241:875-81 (1987) [PubMed] 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_CANLF | ADRA1A | ADRA1C | adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32268.65
Organism:
Dog
Description:
adrenergic Alpha1 0 Dog::O77621
Residue:
295
Sequence:
MVFLSGNASDSSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQITEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPVGGTGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIG
  
Inhibitor
Name:
BDBM50016897
Synonyms:
2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) | 2-(2,6-dichloroanilino)-2-imidazoline | CLONIDINE | N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine | clonidine (amino form)
Type:
Small organic molecule
Emp. Form.:
C9H9Cl2N3
Mol. Mass.:
230.094
SMILES:
Clc1cccc(Cl)c1\[#7]=[#6]-1\[#7]-[#6]-[#6]-[#7]-1
Structure:
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