Reaction Details
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Report a problem with these dataTarget
Muscarinic acetylcholine receptor M2
Ligand
BDBM81466
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1061
Citation
Yamamura, HI; Snyder, SH Muscarinic cholinergic binding in rat brain. Proc Natl Acad Sci U S A 71:1725-9 (1974) [PubMed] Article More Info.:
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51555.53
Organism:
RAT
Description:
P10980
Residue:
466
Sequence:
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
Inhibitor
Name:
BDBM81466
Synonyms:
CAS_23095-76-3 | NSC_6445134 | l-Chlorpheniramine
Type:
Small organic molecule
Emp. Form.:
C10H7ClO4
Mol. Mass.:
226.613
SMILES:
OC(=O)C=CC(=O)Oc1ccc(Cl)cc1 |w:4.4|
Structure:
