Reaction Details Report a problem with these data
Target
Delta-aminolevulinic acid dehydratase
Ligand
BDBM82191
Substrate
n/a
Meas. Tech.
PBGS Assay
pH
8.1±0
Temperature
310.15±0 K
Ki
2.200e+6±n/a nM
Citation
 Stauffer, F; Zizzari, E; Engeloch-Jarret, C; Faurite, JP; Bobálová, J; Neier, R Inhibition studies of porphobilinogen synthase from Escherichia coli differentiating between the two recognition sites. Chembiochem 2:343-54 (2001) [PubMed]  Article 
Target
Name:
Delta-aminolevulinic acid dehydratase
Synonyms:
HEM2_ECOLI | Porphobilinogen synthase | hemB | ncf
Type:
Enzyme
Mol. Mass.:
35617.37
Organism:
Escherichia coli
Description:
P0ACB2
Residue:
324
Sequence:
MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR
  
Inhibitor
Name:
BDBM82191
Synonyms:
Substrate analogue, 8
Type:
Small organic molecule
Emp. Form.:
C5H8O3
Mol. Mass.:
116.1152
SMILES:
CC(=O)CCC(O)=O
Structure:
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