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Target
Delta-aminolevulinic acid dehydratase
Ligand
BDBM50137044
Substrate
n/a
Meas. Tech.
PBGS Assay
pH
8.1±0
Temperature
310.15±0 K
Ki
>1.50000e+8±n/a nM
Citation
 Stauffer, F; Zizzari, E; Engeloch-Jarret, C; Faurite, JP; Bobálová, J; Neier, R Inhibition studies of porphobilinogen synthase from Escherichia coli differentiating between the two recognition sites. Chembiochem 2:343-54 (2001) [PubMed]  Article 
Target
Name:
Delta-aminolevulinic acid dehydratase
Synonyms:
HEM2_ECOLI | Porphobilinogen synthase | hemB | ncf
Type:
Enzyme
Mol. Mass.:
35617.37
Organism:
Escherichia coli
Description:
P0ACB2
Residue:
324
Sequence:
MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR
  
Inhibitor
Name:
BDBM50137044
Synonyms:
Substrate analogue, 16 | [(ammonioacetyl)amino]acetate | glycylglycine
Type:
Small organic molecule
Emp. Form.:
C4H8N2O3
Mol. Mass.:
132.1179
SMILES:
[NH3+]CC(=O)NCC([O-])=O
Structure:
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