Reaction Details
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Report a problem with these dataTarget
Thromboxane A2 receptor
Ligand
BDBM82225
Substrate
n/a
Ki
360±n/a nM
Comments
PDSP_4868
Citation
Armstrong, RA; Jones, RL; Wilson, NH Ligand binding to thromboxane receptors on human platelets: correlation with biological activity. Br J Pharmacol 79:953-64 (1983) [PubMed] Article More Info.:
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_MOUSE | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37114.77
Organism:
MOUSE
Description:
Thromboxane A2 TBXA2R MOUSE::P30987
Residue:
341
Sequence:
MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP
Inhibitor
Name:
BDBM82225
Synonyms:
11,9-epoxymethano PGH2
Type:
Small organic molecule
Emp. Form.:
C20H32O4
Mol. Mass.:
336.4657
SMILES:
CCCCC[C@H](O)\C=C\[C@H]1[C@H]2C[C@H](CO2)[C@@H]1\C=C/CCCC(O)=O |TLB:16:15:11:13.14,THB:8:9:11:13.14|
Structure:
