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Target
Muscarinic acetylcholine receptor M4
Ligand
BDBM50005685
Substrate
n/a
Ki
5.50±n/a nM
Comments
PDSP_3893
Citation
 Lazareno, S; Buckley, NJ; Roberts, FF Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol 38:805-15 (1990) [PubMed] 
Target
Name:
Muscarinic acetylcholine receptor M4
Synonyms:
ACM4_CHICK | CHRM4 | Cholinergic, muscarinic M4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54968.10
Organism:
Chick
Description:
Cholinergic, muscarinic M4 CHRM4 Chick::P17200
Residue:
490
Sequence:
MHNLSAQPWQAKMANLTYDNVTLSNRSEVAIQPPTNYKTVELVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGVFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWILSFILWAPAILFWQFIVGKRTVHERECYIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVRRHKPESRKERKGKSLSFFKAPPVKQNNNNSPKRAVEVKEEVRNGKVDDQPSAQTEATGQQEEKETSNESSTVSMTQTTKDKPTTEILPAGQGQSPAHPRVNPTSKWSKIKIVTKQTGTESVTAIEIVPAKAGASDHNSLSNSRPANVARKFASIARSQVRKKRQMAAREKKVTRTIFAILLAFILTWTPYNVMVLINTFCETCVPETVWSIGYWLCYVNSTINPACYALCNATFKKTFKHLLMCQYRNIGTAR
  
Inhibitor
Name:
BDBM50005685
Synonyms:
2,2-Diphenyl-propionic acid 2-diethylamino-ethyl ester | 2,2-Diphenyl-propionic acid 2-diethylamino-ethyl ester(Aprophen) | 2-(diethylamino)ethyl 2,2-diphenylpropanoate | Aprofene | Aprophen | CHEMBL26505
Type:
Small organic molecule
Emp. Form.:
C21H27NO2
Mol. Mass.:
325.4446
SMILES:
CCN(CC)CCOC(=O)C(C)(c1ccccc1)c1ccccc1
Structure:
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