Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor M4
Ligand
BDBM82373
Substrate
n/a
Ki
117.49±n/a nM
Comments
PDSP_3892
Citation
 Lazareno, S; Buckley, NJ; Roberts, FF Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol 38:805-15 (1990) [PubMed] 
Target
Name:
Muscarinic acetylcholine receptor M4
Synonyms:
ACM4_CHICK | CHRM4 | Cholinergic, muscarinic M4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54968.10
Organism:
Chick
Description:
Cholinergic, muscarinic M4 CHRM4 Chick::P17200
Residue:
490
Sequence:
MHNLSAQPWQAKMANLTYDNVTLSNRSEVAIQPPTNYKTVELVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGVFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWILSFILWAPAILFWQFIVGKRTVHERECYIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVRRHKPESRKERKGKSLSFFKAPPVKQNNNNSPKRAVEVKEEVRNGKVDDQPSAQTEATGQQEEKETSNESSTVSMTQTTKDKPTTEILPAGQGQSPAHPRVNPTSKWSKIKIVTKQTGTESVTAIEIVPAKAGASDHNSLSNSRPANVARKFASIARSQVRKKRQMAAREKKVTRTIFAILLAFILTWTPYNVMVLINTFCETCVPETVWSIGYWLCYVNSTINPACYALCNATFKKTFKHLLMCQYRNIGTAR
  
Inhibitor
Name:
BDBM82373
Synonyms:
DABDMA | diphenylacetoxybutynyl dimethylamine
Type:
n/a
Emp. Form.:
C22H25NO
Mol. Mass.:
319.44
SMILES:
CCN(CC)CC#CCC(=O)C(c1ccccc1)c1ccccc1
Structure:
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