Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 7
Ligand
BDBM30707
Substrate
n/a
Ki
8.31±n/a nM
Comments
PDSP_694
Citation
 Boess, FG; Martin, IL Molecular biology of 5-HT receptors. Neuropharmacology 33:275-317 (1994) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-Hydroxytryptamine receptor 7 (5-HT7) | 5-hydroxytryptamine receptor 7 | 5-hydroxytryptamine receptor 7 (5-HT-7) | 5HT7R_RAT | Adrenergic Alpha | GPRFO | Htr7 | Serotonin (5-HT) receptor | Serotonin Receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
49852.62
Organism:
Rattus norvegicus (rat)
Description:
Rat cloned 5-HT7R.
Residue:
448
Sequence:
MMDVNSSGRPDLYGHLRSLILPEVGRGLQDLSPDGGAHPVVSSWMPHLLSGFLEVTASPAPTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQPESVISLNGVVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERSEFVLQNSDHCGKKGHDT
  
Inhibitor
Name:
BDBM30707
Synonyms:
2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamine | 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine | 2-(5-methoxy-1H-indol-3-yl)ethyl-dimethyl-amine | 3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7257 | MLS000069438 | Methoxydimethyltryptamines | SMR000059066 | WO2023019367, Compound 5-MeO-DMT | cid_1832
Type:
Small organic molecule
Emp. Form.:
C13H18N2O
Mol. Mass.:
218.2948
SMILES:
COc1ccc2[nH]cc(CCN(C)C)c2c1
Structure:
Search PDB for entries with ligand similarity: