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Target
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Ligand
BDBM82733
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay
IC50
13388±803 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay (2011)[AID] 
Target
Name:
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Synonyms:
CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29199.89
Organism:
Homo sapiens (Human)
Description:
gi_10864009
Residue:
261
Sequence:
MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGAPLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEIDGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRESCVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPFFEQLSRVDDVYSVLRQPRPGS
  
Inhibitor
Name:
BDBM82733
Synonyms:
3-chloranyl-N-[(4-methylsulfanylphenyl)methylideneamino]benzamide | 3-chloro-N'-[4-(methylsulfanyl)benzylidene]benzohydrazide | 3-chloro-N-[(4-methylsulfanylphenyl)methylideneamino]benzamide | 3-chloro-N-[[4-(methylthio)benzylidene]amino]benzamide | 3-chloro-N-[[4-(methylthio)phenyl]methylideneamino]benzamide | MLS000704168 | SMR000228646 | cid_693378
Type:
Small organic molecule
Emp. Form.:
C15H13ClN2OS
Mol. Mass.:
304.795
SMILES:
CSc1ccc(C=NNC(=O)c2cccc(Cl)c2)cc1
Structure:
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