Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM80898
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
12200±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM80898
Synonyms:
1-(phenylmethyl)-3-[4-(trifluoromethoxy)phenyl]thiourea | 1-(phenylmethyl)-3-[4-(trifluoromethyloxy)phenyl]thiourea | 1-Benzyl-3-(4-trifluoromethoxy-phenyl)-thiourea | 1-benzyl-3-[4-(trifluoromethoxy)phenyl]thiourea | MLS000591733 | SMR000218741 | cid_948150
Type:
Small organic molecule
Emp. Form.:
C15H13F3N2OS
Mol. Mass.:
326.337
SMILES:
FC(F)(F)Oc1ccc(NC(=S)NCc2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: