Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM80961
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
9270±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM80961
Synonyms:
2-chloranyl-5-(2-fluoren-9-ylidenehydrazinyl)benzoic acid | 2-chloro-5-(2-fluoren-9-ylidenehydrazinyl)benzoic acid | 2-chloro-5-(N'-fluoren-9-ylidenehydrazino)benzoic acid | 2-chloro-5-[2-(9-fluorenylidene)hydrazinyl]benzoic acid | MLS001173792 | SMR000591118 | cid_5114648
Type:
Small organic molecule
Emp. Form.:
C20H13ClN2O2
Mol. Mass.:
348.782
SMILES:
[#8]-[#6](=O)-c1cc(-[#7]\[#7]=[#6]-2/c3ccccc3-c3ccccc-23)ccc1Cl
Structure:
Search PDB for entries with ligand similarity: