Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM83565
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen
EC50
32000±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM83565
Synonyms:
(5Z)-5-[(1-methyl-2-pyrrolyl)methylidene]-3-phenylthiazolidine-2,4-dione | (5Z)-5-[(1-methylpyrrol-2-yl)methylene]-3-phenyl-thiazolidine-2,4-quinone | (5Z)-5-[(1-methylpyrrol-2-yl)methylidene]-3-phenyl-1,3-thiazolidine-2,4-dione | 5-[1-(1-Methyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-3-phenyl-thiazolidine-2,4-dione | MLS000588148 | SMR000220203 | cid_1279053
Type:
Small organic molecule
Emp. Form.:
C15H12N2O2S
Mol. Mass.:
284.333
SMILES:
Cn1cccc1\C=C1/SC(=O)N(C1=O)c1ccccc1
Structure:
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