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Target
Snake venom metalloproteinase BaP1
Ligand
BDBM50239115
Substrate
n/a
Meas. Tech.
ChEMBL_1665241 (CHEMBL4015037)
Kd
34000.00±n/a nM
Citation
 Villalta-Romero, F; Borro, L; Mandic, B; Escalante, T; Rucavado, A; Gutiérrez, JM; Neshich, G; Tasic, L Discovery of small molecule inhibitors for the snake venom metalloprotease BaP1 using in silico and in vitro tests. Bioorg Med Chem Lett 27:2018-2022 (2017) [PubMed]  Article 
Target
Name:
Snake venom metalloproteinase BaP1
Synonyms:
Bap-1 | Hemorrhagic metalloproteinase BaP1 | SVMP | VM1B1_BOTAS
Type:
PROTEIN
Mol. Mass.:
45929.07
Organism:
Bothrops asper
Description:
ChEMBL_840308
Residue:
408
Sequence:
MIEVLLVTICLAVFPYQGSSIILESGNVNDYEVVYPRKVTELPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGRKIITYPSFEDHCYYHGRIENDADSTASISACNGLKGHFKLQGETYLIEPLKLSDSEAHAVYKYENVEKEDEAPKMCGVTETNWESYEPIKKASQSNLTPEQQRFSPRYIELAVVADHGIFTKYNSNLNTIRTRVHEMLNTVNGFYRSVDVHAPLANLEVWSKQDLIKVQKDSSKTLKSFGEWRERDLLPRISHDHAQLLTAVVFDGNTIGRAYTGGMCDPRHSVGVVRDHSKNNLWVAVTMAHELGHNLGIHHDTGSCSCGAKSCIMASVLSKVLSYEFSDCSQNQYETYLTNHNPQCILNKPLLTVSGNELLEAGE
  
Inhibitor
Name:
BDBM50239115
Synonyms:
CHEMBL4082030
Type:
Small organic molecule
Emp. Form.:
C15H16N4O5
Mol. Mass.:
332.3113
SMILES:
CC(C)c1ccc(OCC(=O)N\N=C2/C(=O)NC(=O)N=C2O)cc1 |c:19|
Structure:
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