Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50000570
Substrate
n/a
Meas. Tech.
ChEMBL_149460 (CHEMBL758211)
Ki
63.0±n/a nM
Citation
 Froimowitz, M; Pick, CG; Pasternak, GW Phenylmorphans and analogues: opioid receptor subtype selectivity and effect of conformation on activity. J Med Chem 35:1521-5 (1992) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45038.37
Organism:
CALF
Description:
OPIATE Mu 2 0 CALF::P79350
Residue:
401
Sequence:
MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
  
Inhibitor
Name:
BDBM50000570
Synonyms:
3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol | CHEMBL285250
Type:
Small organic molecule
Emp. Form.:
C15H21NO
Mol. Mass.:
231.3333
SMILES:
CN1CCC2(CCCC1C2)c1cccc(O)c1 |THB:0:1:9:5.7.6|
Structure:
Search PDB for entries with ligand similarity: