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Target
Cathepsin S
Ligand
BDBM50240931
Substrate
n/a
Meas. Tech.
ChEMBL_1669326 (CHEMBL4019214)
IC50
>200000±n/a nM
Citation
 Qi, Q; Obianyo, O; Du, Y; Fu, H; Li, S; Ye, K Blockade of Asparagine Endopeptidase Inhibits Cancer Metastasis. J Med Chem 60:7244-7255 (2017) [PubMed]  Article 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM50240931
Synonyms:
CHEMBL4074941
Type:
Small organic molecule
Emp. Form.:
C14H14N4O2S
Mol. Mass.:
302.352
SMILES:
Cn1c(S)nc2n(C)c(=O)n(Cc3ccccc3)c(=O)c12
Structure:
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