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Target
Vitamin D3 receptor A
Ligand
BDBM50241977
Substrate
n/a
Meas. Tech.
ChEMBL_1671052 (CHEMBL4021081)
EC50
>100±n/a nM
Citation
 Belorusova, AY; Martínez, A; Gándara, Z; Gómez, G; Fall, Y; Rochel, N Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain. Eur J Med Chem 134:86-96 (2017) [PubMed]  Article 
Target
Name:
Vitamin D3 receptor A
Synonyms:
1,25-dihydroxyvitamin D3 receptor A | Nuclear receptor subfamily 1 group I member 1-A | VDR-A | VDRA_DANRE | Vitamin D3 receptor A | nr1i1a | vdr | vdra
Type:
PROTEIN
Mol. Mass.:
50869.54
Organism:
Danio rerio
Description:
ChEMBL_108257
Residue:
453
Sequence:
MLTENSAVNSGGKSKCEAGACESRVNGDATSVMDLMAVSTSATGQDEFDRNAPRICGVCGDKATGFHFNAMTCEGCKGFFRRSMKRKASFTCPFNGNCTITKDNRRHCQACRLKRCIDIGMMKEFILTDEEVQRKKDLIMKRKEEEAAREARKPRLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVREGPVTRSASRAASLHSLSDASSDSFNHSPESVDTKLNFSNLLMMYQDSGSPDSSEEDQQSRLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEVS
  
Inhibitor
Name:
BDBM50241977
Synonyms:
CHEMBL4066758
Type:
Small organic molecule
Emp. Form.:
C28H44O4
Mol. Mass.:
444.6466
SMILES:
[H][C@@]1(CC[C@H](O1)C(C)(C)O)[C@@H](C)[C@@]1([H])CC[C@@]2([H])\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@@H](O)C1=C |r|
Structure:
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