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Target
Gastrin/cholecystokinin type B receptor
Ligand
BDBM50006837
Substrate
n/a
Meas. Tech.
ChEBML_48261
IC50
670.0±n/a nM
Citation
 Yu, MJ; McCowan, JR; Mason, NR; Deeter, JB; Mendelsohn, LG Synthesis and X-ray crystallographic analysis of quinazolinone cholecystokinin/gastrin receptor ligands. J Med Chem 35:2534-42 (1992) [PubMed]  Article 
Target
Name:
Gastrin/cholecystokinin type B receptor
Synonyms:
Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49196.59
Organism:
MOUSE
Description:
Cholecystokinin A CCKBR MOUSE::P56481
Residue:
453
Sequence:
MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCYVQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANTWRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG
  
Inhibitor
Name:
BDBM50006837
Synonyms:
2-[2-(1H-Indol-3-yl)-ethyl]-3-phenyl-3H-quinazolin-4-one | CHEMBL37653
Type:
Small organic molecule
Emp. Form.:
C24H19N3O
Mol. Mass.:
365.4272
SMILES:
O=c1n(c(CCc2c[nH]c3ccccc23)nc2ccccc12)-c1ccccc1
Structure:
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