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Target
Carbonic anhydrase 2
Ligand
BDBM50334354
Substrate
n/a
Meas. Tech.
ChEBML_1685487
Ki
96±n/a nM
Citation
 Angeli, A; Carta, F; Bartolucci, G; Supuran, CT Synthesis of novel acyl selenoureido benzensulfonamides as carbonic anhydrase I, II, VII and IX inhibitors. Bioorg Med Chem 25:3567-3573 (2017) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50334354
Synonyms:
4-(3-(4-fluorophenyl)ureido)benzenesulfonamide | 4-{[(4'-Fluorophenyl)carbamoyl]amino}benzenesulfonamide | 4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide | CHEMBL1615281
Type:
Small organic molecule
Emp. Form.:
C13H12FN3O3S
Mol. Mass.:
309.316
SMILES:
NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1
Structure:
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