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Target
Mu-type opioid receptor
Ligand
BDBM50257773
Substrate
n/a
Meas. Tech.
ChEMBL_1689996 (CHEMBL4040566)
IC50
2320±n/a nM
Citation
 Ravilla, L; Venkata Subba Naidu, N; Dogra, S; Umrao, D; Yadav, PN; Biswas, A; Michael, D; Sekar, K; Nagarajan, K Opioid Receptor Modulators with a Cinnamyl Group. J Med Chem 60:6733-6750 (2017) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50257773
Synonyms:
CHEMBL4081523
Type:
Small organic molecule
Emp. Form.:
C28H36N2O4
Mol. Mass.:
464.5964
SMILES:
CCCC(NC(=O)C(\CN1CCC(C)(C(C)C1)c1cccc(O)c1)=C\c1ccccc1)C(O)=O
Structure:
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