Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50266645
Substrate
n/a
Meas. Tech.
ChEMBL_1701167 (CHEMBL4052149)
Ki
1.3±n/a nM
Citation
 Petrelli, R; Scortichini, M; Kachler, S; Boccella, S; Cerchia, C; Torquati, I; Del Bello, F; Salvemini, D; Novellino, E; Luongo, L; Maione, S; Jacobson, KA; Lavecchia, A; Klotz, KN; Cappellacci, L Exploring the Role of N J Med Chem 60:4327-4341 (2017) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50266645
Synonyms:
CHEMBL4086325
Type:
Small organic molecule
Emp. Form.:
C17H18ClN9O4
Mol. Mass.:
447.836
SMILES:
CCn1nnc(n1)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3ccco3)nc(Cl)nc12 |r|
Structure:
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