Reaction Details Report a problem with these data
Target
High mobility group protein B1
Ligand
BDBM50271261
Substrate
n/a
Meas. Tech.
ChEMBL_1710854 (CHEMBL4120903)
Kd
1.5±n/a nM
Citation
 VanPatten, S; Al-Abed, Y High Mobility Group Box-1 (HMGb1): Current Wisdom and Advancement as a Potential Drug Target. J Med Chem 61:5093-5107 (2018) [PubMed]  Article 
Target
Name:
High mobility group protein B1
Synonyms:
HMG-1 | HMG1 | HMGB1 | HMGB1_HUMAN | High mobility group protein 1
Type:
PROTEIN
Mol. Mass.:
24889.95
Organism:
Homo sapiens (Human)
Description:
ChEMBL_936211
Residue:
215
Sequence:
MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE
  
Inhibitor
Name:
BDBM50271261
Synonyms:
CHEMBL4129393
Type:
Small organic molecule
Emp. Form.:
C9H11NO3
Mol. Mass.:
181.1885
SMILES:
NCCc1cccc(C(O)=O)c1O
Structure:
Search PDB for entries with ligand similarity: