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Target
D(2) dopamine receptor
Ligand
BDBM50016778
Substrate
n/a
Meas. Tech.
ChEBML_58203
Ki
5.2±n/a nM
Citation
 Harrold, MW; Wallace, RA; Farooqui, T; Wallace, LJ; Uretsky, N; Miller, DD Synthesis and D2 dopaminergic activity of pyrrolidinium, tetrahydrothiophenium, and tetrahydrothiophene analogues of sulpiride. J Med Chem 32:874-80 (1989) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2
Type:
Enzyme
Mol. Mass.:
50957.64
Organism:
Mus musculus (Mouse)
Description:
P61168
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50016778
Synonyms:
1-Ethyl-2-[(2-methoxy-5-sulfamoyl-benzoylamino)-methyl]-tetrahydro-thiophenium; iodide | CHEMBL170622
Type:
Small organic molecule
Emp. Form.:
C15H23N2O4S2
Mol. Mass.:
359.484
SMILES:
CC[S+]1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O
Structure:
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