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Target
Trace amine-associated receptor 5
Ligand
BDBM50292711
Substrate
n/a
Meas. Tech.
ChEMBL_1731932 (CHEMBL4147468)
EC50
>10000±n/a nM
Citation
 Guariento, S; Tonelli, M; Espinoza, S; Gerasimov, AS; Gainetdinov, RR; Cichero, E Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists. Eur J Med Chem 146:171-184 (2018) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 5
Synonyms:
Gm227 | TAAR5_MOUSE | TaR-5 | Taar5 | Trace amine receptor 5 | Trace amine-associated receptor 5 | Trimethylamine receptor | mTaar5
Type:
PROTEIN
Mol. Mass.:
38230.08
Organism:
Mus musculus
Description:
ChEMBL_116770
Residue:
337
Sequence:
MRAVLLPGSGEQPTAFCYQVNGSCPRTVHPLAIQVVIYLACAVGVLITVLGNLFVVFAVSYFKVLHTPTNFLLLSLALADMLLGLLVLPLSTVRSVESCWFFGDFLCRLHTYLDTLFCLTSIFHLCFISIDRHCAICDPLLYPSKFTVRTALRYIVAGWGIPAAYTAFFLYTDVVERALSQWLEEMPCVGSCQLLFNKFWGWLNFPAFFVPCLIMISLYLKIFVVATRQAQQIRTLSQSLAGAVKRERKAAKTLGIAVGIYLVCWLPFTVDTLVDSLLNFITPPLVFDIFIWFAYFNSACNPIIYVFSYRWFRKALKLLLSREIFSPRTPTVDLYHD
  
Inhibitor
Name:
BDBM50292711
Synonyms:
CHEMBL3628707
Type:
Small organic molecule
Emp. Form.:
C12H18N6
Mol. Mass.:
246.3115
SMILES:
NC(=N)NC(=N)N1CCN(CC1)c1ccccc1
Structure:
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