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Target
Dopamine beta-hydroxylase
Ligand
BDBM50017834
Substrate
n/a
Meas. Tech.
ChEBML_59142
Ki
57000.0±n/a nM
Citation
 Farrington, GK; Kumar, A; Villafranca, JJ Benzofurans as mechanism-based inhibitors of dopamine beta-hydroxylase. J Med Chem 32:735-7 (1989) [PubMed]  Article 
Target
Name:
Dopamine beta-hydroxylase
Synonyms:
DBH | DOPO_BOVIN
Type:
PROTEIN
Mol. Mass.:
68136.39
Organism:
Bos taurus
Description:
ChEMBL_50738
Residue:
610
Sequence:
MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISYAQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDSQQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSGLHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIVMYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRFLRLEVHYHNPLVITGRRDSSGIRLYYTAALRRFDAGIMELGLAYTPVMAIPPQETAFVLTGYCTDKCTQLALPASGIHIFASQLHTHLTGRKVVTVLARDGRETEIVNRDNHYSPHFQEIRMLKKVVSVQPGDVLITSCTYNTEDRRLATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDPGFLHKYFRLVNRFNSEEVCTCPQASVPEQFASVPWNSFNREVLKALYGFAPISMHCNRSSAVRFQGEWNRQPLPEIVSRLEEPTPHCPASQAQSPAGPTVLNISGGKG
  
Inhibitor
Name:
BDBM50017834
Synonyms:
4-(1-Aminomethyl-prop-2-ynyl)-phenol | CHEMBL163120
Type:
Small organic molecule
Emp. Form.:
C10H11NO
Mol. Mass.:
161.2004
SMILES:
NCC(C#C)c1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: