Reaction Details Report a problem with these data
Target
Chymotrypsin-C
Ligand
BDBM50018175
Substrate
n/a
Meas. Tech.
ChEMBL_49776 (CHEMBL662998)
pH
5±n/a
Ki
48000±n/a nM
Comments
extracted
Citation
 Silver, MS; Haskell, JH Acid-sensitive latent inhibitors for proteolytic enzymes: synthesis and characterization. J Med Chem 32:1253-9 (1989) [PubMed]  Article 
Target
Name:
Chymotrypsin-C
Synonyms:
CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C
Type:
Enzyme
Mol. Mass.:
29487.98
Organism:
Homo sapiens (Human)
Description:
Q99895
Residue:
268
Sequence:
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
  
Inhibitor
Name:
BDBM50018175
Synonyms:
CHEMBL22389 | N-{1-Benzyl-2-[(pyridine-3-carbonyl)-hydrazono]-ethyl}-benzamide
Type:
Small organic molecule
Emp. Form.:
C22H20N4O2
Mol. Mass.:
372.4198
SMILES:
O=C(NN=CC(Cc1ccccc1)NC(=O)c1ccccc1)c1cccnc1 |w:3.2|
Structure:
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