Reaction Details Report a problem with these data
Target
Proteasome subunit beta type-2
Ligand
BDBM50453683
Substrate
n/a
Meas. Tech.
ChEMBL_1750245 (CHEMBL4185005)
Ki
6710±n/a nM
Citation
  TBA Bioorg Med Chem Lett 28:278-283 (2018) [PubMed]  Article 
Target
Name:
Proteasome subunit beta type-2
Synonyms:
20S proteasome | PSB2_HUMAN | PSMB2 | Proteasome Macropain subunit
Type:
PROTEIN
Mol. Mass.:
22837.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1294233
Residue:
201
Sequence:
MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRIIDKNGIHDLDNISFPKQGS
  
Inhibitor
Name:
BDBM50453683
Synonyms:
CHEMBL4208777
Type:
Small organic molecule
Emp. Form.:
C17H14N2O3S
Mol. Mass.:
326.37
SMILES:
COc1cc(\C=C2/NC(=S)N(C2=O)c2ccccc2)ccc1O
Structure:
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