Reaction Details Report a problem with these data
Target
Iron-starvation protein PigA
Ligand
BDBM50455269
Substrate
n/a
Meas. Tech.
ChEMBL_1754112 (CHEMBL4188872)
Kd
1200±n/a nM
Citation
 Liang, D; Robinson, E; Hom, K; Yu, W; Nguyen, N; Li, Y; Zong, Q; Wilks, A; Xue, F Structure-based design and biological evaluation of inhibitors of the pseudomonas aeruginosa heme oxygenase (pa-HemO). Bioorg Med Chem Lett 28:1024-1029 (2018) [PubMed]  Article 
Target
Name:
Iron-starvation protein PigA
Synonyms:
Heme oxygenase | Iron-starvation protein PigA
Type:
PROTEIN
Mol. Mass.:
21946.19
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_444781
Residue:
198
Sequence:
MDTLAPESTRQNLRSQRLNLLTNEPHQRLESLVKSKEPFASRDNFARFVAAQYLFQHDLEPLYRNEALARLFPGLASRARDDAARADLADLGHPVPEGDQSVREADLSLAEALGWLFVSEGSKLGAAFLFKKAAALELDENFGARHLAEPEGGRAQGWKSFVAILDGIELNEEEERLAAKGASDAFNRFGDLLERTFA
  
Inhibitor
Name:
BDBM50455269
Synonyms:
CHEMBL4205009
Type:
Small organic molecule
Emp. Form.:
C19H16N2O3S2
Mol. Mass.:
384.472
SMILES:
OC(=O)CCN1C(=S)S\C(=C/c2cccc(Nc3ccccc3)c2)C1=O
Structure:
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