Reaction Details Report a problem with these data
Target
Steroid hormone receptor ERR2
Ligand
BDBM50455427
Substrate
n/a
Meas. Tech.
ChEMBL_1754410 (CHEMBL4189170)
EC50
20±n/a nM
Citation
 Lin, H; Doebelin, C; Patouret, R; Garcia-Ordonez, RD; Chang, MR; Dharmarajan, V; Bayona, CR; Cameron, MD; Griffin, PR; Kamenecka, TM Design, synthesis, and evaluation of simple phenol amides as ERR? agonists. Bioorg Med Chem Lett 28:1313-1319 (2018) [PubMed]  Article 
Target
Name:
Steroid hormone receptor ERR2
Synonyms:
ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 Beta
Type:
PROTEIN
Mol. Mass.:
48061.77
Organism:
Homo sapiens (Human)
Description:
ChEMBL_11254
Residue:
433
Sequence:
MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEMLEAKV
  
Inhibitor
Name:
BDBM50455427
Synonyms:
CHEMBL4206963
Type:
Small organic molecule
Emp. Form.:
C20H25NO2
Mol. Mass.:
311.418
SMILES:
Cc1cc(O)ccc1C(=O)NCCc1ccc(cc1)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: