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Target
Envelope glycoprotein
Ligand
BDBM58492
Substrate
n/a
Meas. Tech.
ChEMBL_1755049 (CHEMBL4189809)
Kd
16000±n/a nM
Citation
 Zhao, Y; Ren, J; Fry, EE; Xiao, J; Townsend, AR; Stuart, DI Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs. J Med Chem 61:4938-4945 (2018) [PubMed]  Article 
Target
Name:
Envelope glycoprotein
Synonyms:
Envelope glycoprotein | GP | GP1 | GP1,2 | GP1,2-delta | GP2 | Shed GP | VGP_EBOZM
Type:
PROTEIN
Mol. Mass.:
74464.56
Organism:
Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus)
Description:
ChEMBL_117434
Residue:
676
Sequence:
MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFTVVSNGAKNISGQSPARTSSDPGTNTTTEDHKIMASENSSAMVQVHSQGREAAVSHLTTLATISTSPQSLTTKPGPDNSTHNTPVYKLDISEATQVEQHHRRTDNDSTASDTPSATTAAGPPKAENTNTSKSTDFLDPATTTSPQNHSETAGNNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRTRREAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDFVDKTLPDQGDNDNWWTGWRQWIPAGIGVTGVIIAVIALFCICKFVF
  
Inhibitor
Name:
BDBM58492
Synonyms:
2-[4-[(Z)-4-chloranyl-1,2-diphenyl-but-1-enyl]phenoxy]-N,N-dimethyl-ethanamine;2-oxidanylpropane-1,2,3-tricarboxylic acid | 2-[4-[(Z)-4-chloro-1,2-diphenyl-but-1-enyl]phenoxy]ethyl-dimethyl-amine;citric acid | 2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid | MLS001424189 | SMR000469213 | TOREMIFENE | TOREMIFENE CITRATE | cid_3005572 | med.21724, Compound Toremifene
Type:
Small organic molecule
Emp. Form.:
C26H28ClNO
Mol. Mass.:
405.96
SMILES:
CN(C)CCOc1ccc(cc1)C(=C(\CCCl)c1ccccc1)\c1ccccc1
Structure:
Search PDB for entries with ligand similarity: