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Target
Glutathione S-transferase omega-1
Ligand
BDBM225702
Substrate
n/a
Meas. Tech.
ChEMBL_1764010 (CHEMBL4199257)
IC50
1020000±n/a nM
Citation
 Xie, Y; Dahlin, JL; Oakley, AJ; Casarotto, MG; Board, PG; Baell, JB Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem 61:7448-7470 (2018) [PubMed]  Article 
Target
Name:
Glutathione S-transferase omega-1
Synonyms:
GSTO 1-1 | GSTO1 | GSTO1_HUMAN | GSTTLP28 | Glutathione S-transferase omega-1 | Glutathione transferase omega 1 | glutathione S-transferase omega-1 isoform 1
Type:
PROTEIN
Mol. Mass.:
27565.54
Organism:
Homo sapiens (Human)
Description:
EBI_11172
Residue:
241
Sequence:
MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
  
Inhibitor
Name:
BDBM225702
Synonyms:
CS331
Type:
Small Organic Molecule
Emp. Form.:
C24H39O4
Mol. Mass.:
391.5646
SMILES:
C[C@H](CCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
Structure:
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