Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50458543
Substrate
n/a
Meas. Tech.
ChEMBL_1764067 (CHEMBL4199314)
Ki
67±n/a nM
Citation
 Trivedi-Parmar, V; Jorgensen, WL Advances and Insights for Small Molecule Inhibition of Macrophage Migration Inhibitory Factor. J Med Chem 61:8104-8119 (2018) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50458543
Synonyms:
CHEMBL4208079
Type:
Small organic molecule
Emp. Form.:
C29H28FN3O5
Mol. Mass.:
517.5481
SMILES:
OC(=O)c1cc(ccc1Oc1cccc(c1)-c1ccc(OCCCN2CCOCC2)cc1)-c1c[nH]nc1F
Structure:
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