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Target
Pepsin A
Ligand
BDBM50022293
Substrate
n/a
Meas. Tech.
ChEBML_154015
Ki
2.5±n/a nM
Citation
 Holladay, MW; Salituro, FG; Rich, DH Synthetic and enzyme inhibition studies of pepstatin analogues containing hydroxyethylene and ketomethylene dipeptide isosteres. J Med Chem 30:374-83 (1987) [PubMed]  Article 
Target
Name:
Pepsin A
Synonyms:
PEPA_PIG | PGA | Pepsin | Pepsin A precursor
Type:
Enzyme
Mol. Mass.:
41232.87
Organism:
Porcine
Description:
n/a
Residue:
385
Sequence:
MKWLLLLSLVVLSECLVKVPLVRKKSLRQNLIKNGKLKDFLKTHKHNPASKYFPEAAALIGDEPLENYLDTEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACSDHNQFNPDDSSTFEATSQELSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISASGATPVFDNLWDQGLVSQDLFSVYLSSNDDSGSVVLLGGIDSSYYTGSLNWVPVSVEGYWQITLDSITMDGETIACSGGCQAIVDTGTSLLTGPTSAIANIQSDIGASENSDGEMVISCSSIDSLPDIVFTINGVQYPLSPSAYILQDDDSCTSGFEGMDVPTSSGELWILGDVFIRQYYTVFDRANNKVGLAPVA
  
Inhibitor
Name:
BDBM50022293
Synonyms:
CHEMBL124266 | N-(2-Hydroxy-1-isobutyl-4-{1-[1-(3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-phenyl-ethylamino}-butyl)-3-methyl-2-(3-methyl-butyrylamino)-butyramide
Type:
Small organic molecule
Emp. Form.:
C34H58N4O5
Mol. Mass.:
602.8481
SMILES:
CC(C)CCNC(=O)C(C)NC(=O)C(C[C@H](O)[C@H](CC(C)C)NC(=O)C(NC(=O)CC(C)C)C(C)C)Cc1ccccc1
Structure:
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