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Target
Sialidase-3
Ligand
BDBM50465961
Substrate
n/a
Meas. Tech.
ChEMBL_1789502 (CHEMBL4261236)
IC50
7200±n/a nM
Citation
 Guo, T; Héon-Roberts, R; Zou, C; Zheng, R; Pshezhetsky, AV; Cairo, CW Selective Inhibitors of Human Neuraminidase 1 (NEU1). J Med Chem 61:11261-11279 (2018) [PubMed]  Article 
Target
Name:
Sialidase-3
Synonyms:
NEU3 | NEUR3_HUMAN | Sialidase 3 | Sialidase-3
Type:
PROTEIN
Mol. Mass.:
48257.99
Organism:
Homo sapiens (Human)
Description:
ChEMBL_461856
Residue:
428
Sequence:
MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRRGLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSGRNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYTYYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVLYCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSSKDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRPWILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGRNPSQFKSN
  
Inhibitor
Name:
BDBM50465961
Synonyms:
CHEMBL4279510
Type:
Small organic molecule
Emp. Form.:
C20H25N3O9
Mol. Mass.:
451.4272
SMILES:
[H][C@]1(OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CNC(=O)c1ccc(NC(C)=O)cc1 |r,c:3|
Structure:
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