Reaction Details Report a problem with these data
Target
Chymotrypsinogen A
Ligand
BDBM50026011
Substrate
n/a
Meas. Tech.
ChEBML_49944
Ki
30800000±n/a nM
Citation
 Thompson, SA; Andrews, PR; Hanzlik, RP Carboxyl-modified amino acids and peptides as protease inhibitors. J Med Chem 29:104-11 (1986) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50026011
Synonyms:
(E)-4-Acetylamino-5-phenyl-pent-2-enoic acid methyl ester | 4-Acetylamino-5-phenyl-pent-2-enoic acid methyl ester | CHEMBL12829
Type:
Small organic molecule
Emp. Form.:
C14H17NO3
Mol. Mass.:
247.2897
SMILES:
COC(=O)\C=C\C(Cc1ccccc1)NC(C)=O
Structure:
Search PDB for entries with ligand similarity: