Reaction Details Report a problem with these data
Target
Papain
Ligand
BDBM50026019
Substrate
n/a
Meas. Tech.
ChEBML_152507
Ki
26000±n/a nM
Citation
 Thompson, SA; Andrews, PR; Hanzlik, RP Carboxyl-modified amino acids and peptides as protease inhibitors. J Med Chem 29:104-11 (1986) [PubMed]  Article 
Target
Name:
Papain
Synonyms:
Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I
Type:
Enzyme
Mol. Mass.:
38923.01
Organism:
Carica papaya
Description:
Papain was purchased from Sigma, Germany.
Residue:
345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
  
Inhibitor
Name:
BDBM50026019
Synonyms:
4-(2-Acetylamino-3-phenyl-propionylamino)-but-2-enoic acid methyl ester | CHEMBL274617
Type:
Small organic molecule
Emp. Form.:
C16H20N2O4
Mol. Mass.:
304.341
SMILES:
COC(=O)\C=C\CNC(=O)C(Cc1ccccc1)NC(C)=O
Structure:
Search PDB for entries with ligand similarity: