Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM50026216
Substrate
n/a
Meas. Tech.
ChEBML_49275
IC50
1500±n/a nM
Citation
 Mistry, JS; Abraham, DJ; Hanin, I Neurochemistry of aging. 1. Toxins for an animal model of Alzheimer's disease. J Med Chem 29:376-80 (1986) [PubMed]  Article 
Target
Name:
High affinity choline transporter 1
Synonyms:
Choline transporter | Cht1 | SC5A7_MOUSE | Slc5a7
Type:
PROTEIN
Mol. Mass.:
63358.06
Organism:
Mus musculus
Description:
ChEMBL_644789
Residue:
580
Sequence:
MSFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYSDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM50026216
Synonyms:
1-Ethyl-1-(2-hydroxy-ethyl)-aziridinium; chloride | CHEMBL125756
Type:
Small organic molecule
Emp. Form.:
C6H14NO
Mol. Mass.:
116.1809
SMILES:
CC[N+]1(CCO)CC1
Structure:
Search PDB for entries with ligand similarity: