Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50037454
Substrate
n/a
Meas. Tech.
ChEMBL_211352 (CHEMBL873906)
IC50
370±n/a nM
Citation
 Li, L; Wang, HK; Kuo, SC; Wu, TS; Mauger, A; Lin, CM; Hamel, E; Lee, KH Antitumor agents. 155. Synthesis and biological evaluation of 3',6,7-substituted 2-phenyl-4-quinolones as antimicrotubule agents. J Med Chem 37:3400-7 (1994) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50037454
Synonyms:
6-(3-Chloro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one | CHEMBL50809
Type:
Small organic molecule
Emp. Form.:
C16H10ClNO3
Mol. Mass.:
299.708
SMILES:
Oc1cc(nc2cc3OCOc3cc12)-c1cccc(Cl)c1
Structure:
Search PDB for entries with ligand similarity: