Reaction Details Report a problem with these data
Target
UDP-galactopyranose mutase
Ligand
BDBM53451
Substrate
n/a
Meas. Tech.
ChEMBL_312805 (CHEMBL837765)
IC50
168000±n/a nM
Citation
 Tangallapally, RP; Yendapally, R; Lee, RE; Hevener, K; Jones, VC; Lenaerts, AJ; McNeil, MR; Wang, Y; Franzblau, S; Lee, RE Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. J Med Chem 47:5276-83 (2004) [PubMed]  Article 
Target
Name:
UDP-galactopyranose mutase
Synonyms:
GLF_MYCTU | UDP-galactopyranose mutase | Uridine 5'-diphosphate-galactopyranose mutase (UGM) | glf
Type:
Protein
Mol. Mass.:
45807.82
Organism:
Mycobacterium tuberculosis H37Rv
Description:
P9WIQ1
Residue:
399
Sequence:
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
  
Inhibitor
Name:
BDBM53451
Synonyms:
MLS001163735 | N-(1-adamantyl)-5-nitro-2-furamide | N-(1-adamantyl)-5-nitro-2-furancarboxamide | N-(1-adamantyl)-5-nitro-furan-2-carboxamide | N-(1-adamantyl)-5-nitrofuran-2-carboxamide | N-1-adamantyl-5-nitro-2-furamide | O-acyl oxime isatin derivative, 37 | SMR000498736 | cid_2994355
Type:
Small organic molecule
Emp. Form.:
C15H18N2O4
Mol. Mass.:
290.3144
SMILES:
[H]C12CC3([H])CC([H])(C1)CC(C2)(C3)NC(=O)c1ccc(o1)[N+]([O-])=O |TLB:8:6:12:1.11.2,5:3:11:6.9.8,THB:5:6:11:3.12.2|
Structure:
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