Reaction Details Report a problem with these data
Target
UDP-galactopyranose mutase
Ligand
BDBM50475086
Substrate
n/a
Meas. Tech.
ChEMBL_312805 (CHEMBL837765)
IC50
392000±n/a nM
Citation
 Tangallapally, RP; Yendapally, R; Lee, RE; Hevener, K; Jones, VC; Lenaerts, AJ; McNeil, MR; Wang, Y; Franzblau, S; Lee, RE Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. J Med Chem 47:5276-83 (2004) [PubMed]  Article 
Target
Name:
UDP-galactopyranose mutase
Synonyms:
GLF_MYCTU | UDP-galactopyranose mutase | Uridine 5'-diphosphate-galactopyranose mutase (UGM) | glf
Type:
Protein
Mol. Mass.:
45807.82
Organism:
Mycobacterium tuberculosis H37Rv
Description:
P9WIQ1
Residue:
399
Sequence:
MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
  
Inhibitor
Name:
BDBM50475086
Synonyms:
CHEMBL363736
Type:
Small organic molecule
Emp. Form.:
C12H7N3O4
Mol. Mass.:
257.2017
SMILES:
[O-][N+](=O)c1ccc(o1)C(=O)Nc1ccc(cc1)C#N
Structure:
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