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Target
Transporter
Ligand
BDBM50020707
Substrate
n/a
Meas. Tech.
ChEMBL_129897 (CHEMBL740142)
IC50
1500±n/a nM
Citation
 Högberg, T; Ulff, B; Renyi, AL; Ross, SB Synthesis of pyridylallylamines related to zimelidine and their inhibition of neuronal monoamine uptake. J Med Chem 24:1499-507 (1982) [PubMed]  Article 
Target
Name:
Transporter
Synonyms:
Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters
Type:
PROTEIN
Mol. Mass.:
66787.87
Organism:
Rattus norvegicus
Description:
ChEMBL_1463061
Residue:
597
Sequence:
MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
  
Inhibitor
Name:
BDBM50020707
Synonyms:
CHEMBL287064 | Nomelidine | Norzimelidine | [3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-methyl-amine(norzimeldine) | cis -[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-methyl-amine ;C2H4O4 | trans-[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-methyl-amine;C2H4O4
Type:
Small organic molecule
Emp. Form.:
C15H15BrN2
Mol. Mass.:
303.197
SMILES:
CNC\C=C(\c1ccc(Br)cc1)c1cccnc1
Structure:
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