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Target
Pre-mRNA-processing factor 19
Ligand
BDBM50479365
Substrate
n/a
Meas. Tech.
ChEMBL_536041 (CHEMBL991611)
EC50
524±n/a nM
Citation
 Alvarado, M; Goya, P; Macías-González, M; Pavón, FJ; Serrano, A; Jagerovic, N; Elguero, J; Gutiérrez-Rodríguez, A; García-Granda, S; Suardíaz, M; Rodríguez de Fonseca, F Antiobesity designed multiple ligands: Synthesis of pyrazole fatty acid amides and evaluation as hypophagic agents. Bioorg Med Chem 16:10098-105 (2008) [PubMed]  Article 
Target
Name:
Pre-mRNA-processing factor 19
Synonyms:
2.3.2.27 | PRP19 | PRP19_YEAST | PSO4 | PSO4 | Pre-mRNA-processing factor 19 | RING-type E3 ubiquitin transferase PRP19
Type:
PROTEIN
Mol. Mass.:
56556.80
Organism:
Saccharomyces cerevisiae S288c
Description:
ChEMBL_100887
Residue:
503
Sequence:
MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQASLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAKLVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP
  
Inhibitor
Name:
BDBM50479365
Synonyms:
CHEMBL457440
Type:
Small organic molecule
Emp. Form.:
C34H45Cl2N3O
Mol. Mass.:
582.647
SMILES:
CCCCCCCC\C=C/CCCCCCCCNC(=O)c1cc(-c2ccc(Cl)cc2)n(n1)-c1ccc(Cl)cc1
Structure:
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