Reaction Details Report a problem with these data
Target
Genome polyprotein
Ligand
BDBM50482347
Substrate
n/a
Meas. Tech.
ChEMBL_642270 (CHEMBL1177150)
Ki
390±n/a nM
Citation
Lampa, A; Ehrenberg, AE; Gustafsson, SS; Vema, A; Kerblom, E; Lindeberg, G; Karlén, A; Danielson, UH; Sandström, A Improved P2 phenylglycine-based hepatitis C virus NS3 protease inhibitors with alkenylic prime-side substituents. Bioorg Med Chem 18:5413-24 (2010) [PubMed] Article
More Info.:
Target
Name:
Genome polyprotein
Synonyms:
Protease NS3/Non-structural protein 4A (NS3/NS4A) | Protease NS3/Non-structural protein 4A (NS3/NS4A) (D168V)
Type:
Enzyme
Mol. Mass.:
19121.30
Organism:
Hepatitis C virus genotype 1b (isolate Con1) (HCV)
Description:
Q91RS4
Residue:
181
Sequence:
APITAYAQQTRGLLGCIITSLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAGTRTIASPKGPVIQMYTNVDQDLVGWPAPQGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGLFRAAVCTRGVAKAVDFIPVENLETTMRS