Reaction Details Report a problem with these data
Target
Cytochrome c
Ligand
BDBM50486085
Substrate
n/a
Meas. Tech.
ChEMBL_887090 (CHEMBL2214315)
EC50
14400±n/a nM
Citation
 Moure, A; Orzáez, M; Sancho, M; Messeguer, A Synthesis of enantiomerically pure perhydro-1,4-diazepine-2,5-dione and 1,4-piperazine-2,5-dione derivatives exhibiting potent activity as apoptosis inhibitors. Bioorg Med Chem Lett 22:7097-9 (2012) [PubMed]  Article 
Target
Name:
Cytochrome c
Synonyms:
CYC | CYCS | CYC_HUMAN | Cytochrome c
Type:
PROTEIN
Mol. Mass.:
11759.18
Organism:
Homo sapiens
Description:
ChEMBL_117061
Residue:
105
Sequence:
MGDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE
  
Inhibitor
Name:
BDBM50486085
Synonyms:
CHEMBL2203816
Type:
Small organic molecule
Emp. Form.:
C39H38Cl4N4O4
Mol. Mass.:
768.555
SMILES:
NC(=O)CN(CCc1ccc(Cl)cc1Cl)C(=O)[C@H]1CC(=O)N(CCc2ccc(Cl)cc2Cl)CC(=O)N1CCC(c1ccccc1)c1ccccc1 |r|
Structure:
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