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Target
Type-1 angiotensin II receptor
Ligand
BDBM50047801
Substrate
n/a
Meas. Tech.
ChEMBL_901575 (CHEMBL3068556)
IC50
1700±n/a nM
Citation
  TBA Med Chem Res 21:2307-2315 (2012)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41009.15
Organism:
RABBIT
Description:
ANGIOTENSIN AT1 AGTR1 RABBIT::P34976
Residue:
359
Sequence:
MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
  
Inhibitor
Name:
BDBM50047801
Synonyms:
CHEMBL345894 | N-[4-(3-Butyl-5-pyridin-3-yl-[1,2,4]triazol-4-ylmethyl)-phenyl]-phthalamic acid
Type:
Small organic molecule
Emp. Form.:
C26H25N5O3
Mol. Mass.:
455.5084
SMILES:
CCCCc1nnc(-c2cccnc2)n1Cc1ccc(NC(=O)c2ccccc2C(O)=O)cc1
Structure:
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