Reaction Details Report a problem with these data
Target
Cytochrome b
Ligand
BDBM50487147
Substrate
n/a
Meas. Tech.
ChEMBL_908680 (CHEMBL3066175)
Ki
298±n/a nM
Citation
 Zhao, PL; Wang, L; Zhu, XL; Huang, X; Zhan, CG; Wu, JW; Yang, GF Subnanomolar inhibitor of cytochrome bc1 complex designed by optimizing interaction with conformationally flexible residues. J Am Chem Soc 132:185-94 (2010) [PubMed]  Article 
Target
Name:
Cytochrome b
Synonyms:
COB | CYB_PIG | CYTB | Complex III subunit 3 | Complex III subunit III | Cytochrome b | Cytochrome b-c1 complex subunit 3 | MT-CYB | MTCYB | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Type:
PROTEIN
Mol. Mass.:
42786.51
Organism:
Sus scrofa
Description:
ChEMBL_106569
Residue:
379
Sequence:
MTNIRKSHPLMKIINNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWVIRYLHANGASMFFICLFIHVGRGLYYGSYMFLETWNIGVVLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIITALAAVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGALFMMLILLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVASILILILMPMLHTSKQRGMMFRPLSQCLFWMLVADLITLTWIGGQPVEHPFIIIGQLASILYFLIILVLMPITSIIENNLLKW
  
Inhibitor
Name:
BDBM50487147
Synonyms:
AZOXYSTROBIN | CHEBI:40909 | DNDI1511705 | TCMDC-125883
Type:
Small organic molecule
Emp. Form.:
C22H17N3O5
Mol. Mass.:
403.3875
SMILES:
CO\C=C(\C(=O)OC)c1ccccc1Oc1cc(Oc2ccccc2C#N)ncn1
Structure:
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