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Target
Transporter
Ligand
BDBM50031343
Substrate
n/a
Meas. Tech.
ChEMBL_143118 (CHEMBL748000)
Ki
5±n/a nM
Citation
 Ma, S; Lin, L; Raghavan, R; Cohenour, P; Lin, PY; Bennett, J; Lewis, RJ; Enwall, EL; Kostrzewa, R; Lehr, RE In vivo and in vitro studies on the neurotoxic potential of 6-hydroxydopamine analogs. J Med Chem 38:4087-97 (1995) [PubMed]  Article 
Target
Name:
Transporter
Synonyms:
Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters
Type:
PROTEIN
Mol. Mass.:
66787.87
Organism:
Rattus norvegicus
Description:
ChEMBL_1463061
Residue:
597
Sequence:
MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
  
Inhibitor
Name:
BDBM50031343
Synonyms:
2-Amino-5-(2-amino-ethyl)-benzene-1,4-diol | CHEMBL130653
Type:
Small organic molecule
Emp. Form.:
C8H12N2O2
Mol. Mass.:
168.1931
SMILES:
NCCc1cc(O)c(N)cc1O
Structure:
Search PDB for entries with ligand similarity: