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Target
Type-1 angiotensin II receptor
Ligand
BDBM50044402
Substrate
n/a
Meas. Tech.
ChEMBL_910709 (CHEMBL3056264)
IC50
550±n/a nM
Citation
  TBA Med Chem Res 19:177-185 (2010)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor
Type:
PROTEIN
Mol. Mass.:
41107.81
Organism:
Bos taurus
Description:
ChEMBL_36779
Residue:
359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFKIILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
  
Inhibitor
Name:
BDBM50044402
Synonyms:
2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid | 2-Butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid(CV11194) | CHEMBL48242
Type:
Small organic molecule
Emp. Form.:
C26H24N6O2
Mol. Mass.:
452.5078
SMILES:
CCCCc1nc2cccc(C(O)=O)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Structure:
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