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Target
Trehalase
Ligand
BDBM50487999
Substrate
n/a
Meas. Tech.
ChEMBL_916861 (CHEMBL3082109)
IC50
891250±n/a nM
Citation
 Qian, X; Liu, Z; Li, Z; Li, Z; Song, G Synthesis and quantitative structure-activity relationships of fluorine-containing 4,4-dihydroxylmethyl-2-aryliminooxazo(thiazo)lidines as trehalase inhibitors. J Agric Food Chem 49:5279-84 (2001) [PubMed]  Article 
Target
Name:
Trehalase
Synonyms:
Alpha-trehalose glucohydrolase | TREH
Type:
PROTEIN
Mol. Mass.:
66445.51
Organism:
Sus scrofa
Description:
ChEMBL_105438
Residue:
583
Sequence:
MQRRTWGLHLLLLLGLGLGSWEALPPPCESQIYCHGELLRQVQMARLYQDDKQFVDMPLSVAPDQVLQRFSELAQAHNFSIPQQELQDFIREHFQAVGQELQPWTPEDWKDSPQFLQKILDPKLRAWAGQLHQLWKKLGKKVKPEVLSHPERFSLIYSGHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMPGTVKGMLQNFLDLVQTYGHVPNGARVYYLQRSQPPLLSLMMERYVTQANDTAFLRDNLETLALELDFWTKNRSISVSSGGKSYVLNRYHVPYGGPRPESYSKDAELAATLSEGDHEALWAELKAGAESGWDFSSRWFVGGPNPDSLSSIRTSKLVPVDLNAFLCQAEELMSNFYSRLGNDSQAEKYRNLRAQRMAAMKDILWDEEKGAWFDYDLENGKKNLEFYPSNLAPLWAGCFSDPGDVDKALKYLEDSQILTYHYGIPTSLRKTGQQWDFPNAWAPLQDLVIRGLAKSPSARAQEVAFQLAQNWIRTNFDVYSRRSAMYEKYDISNGGQPGGGGEYEVQEGFGWTNGVVLMLLDRYGDRLSSGTQTVFLEPHCLTAALLLGLMLSLLPQ
  
Inhibitor
Name:
BDBM50487999
Synonyms:
CHEMBL2270663
Type:
Small organic molecule
Emp. Form.:
C11H12F2N2O3
Mol. Mass.:
258.2214
SMILES:
OCC1(CO)CO\C(N1)=N/c1ccc(F)cc1F
Structure:
Search PDB for entries with ligand similarity: