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Target
Mu-type opioid receptor
Ligand
BDBM50033643
Substrate
n/a
Meas. Tech.
ChEBML_136067
IC50
104±n/a nM
Citation
 Sebastian, A; Bidlack, JM; Jiang, Q; Deecher, D; Teitler, M; Glick, SD; Archer, S 14 beta-[(p-nitrocinnamoyl)amino]morphinones, 14 beta-[(p-nitrocinnamoyl)amino]-7,8-dihydromorphinones, and their codeinone analogues: synthesis and receptor activity. J Med Chem 36:3154-60 (1993) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | Mu opioid receptor | OPIATE Mu | OPRM1 | OPRM_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45038.37
Organism:
CALF
Description:
OPIATE Mu 2 0 CALF::P79350
Residue:
401
Sequence:
MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
  
Inhibitor
Name:
BDBM50033643
Synonyms:
1N-[10-methoxy-4,13-dimethyl-14-oxo-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-17-yl]-4-(4-nitrophenyl)-(Z)-2-butenamide | CHEMBL320060
Type:
Small organic molecule
Emp. Form.:
C28H29N3O6
Mol. Mass.:
503.5464
SMILES:
COc1ccc2CC3N(C)CCC45c2c1O[C@@]4(C)C(=O)CC[C@@]35NC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O |TLB:23:22:13.5.6:8.11.10,THB:9:8:22:13.5.6,14:13:22:8.11.10|
Structure:
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